O’Brien et al. (2023). Medicinal cannabis for pain: Real-world data on three-month changes in symptoms and quality of life. Journal of Cannabis Research.
Relevance: Provides real-world data from Project Twenty21 Australia, showing improvements in pain severity, quality of life, sleep, and mood in chronic pain patients using medical cannabis over three months. Useful for demonstrating patient-reported outcomes and holistic benefits.journals.sagepub.com
Jylkkä et al. (2023). The holistic effects of medical cannabis compared to opioids on pain experience in Finnish patients with chronic pain. Journal of Cannabis Research, 5, 38.
Relevance: Compares medical cannabis to opioids, finding cannabis users report higher positive emotional and holistic effects (e.g., improved mood, focus, and clarity) with no significant difference in side effects. Valuable for contrasting cannabis with traditional treatments.jcannabisresearch.biomedcentral.com
McMahon et al. (2023). Perceived Effectiveness of Medical Cannabis Among Adults with Chronic Pain: Findings from Interview Data in a Three-Month Pilot Study. Cannabis, 6(2), 62–75.
Hameed et al. (2023). Medical Cannabis for Chronic Nonmalignant Pain Management. Current Pain and Headache Reports, 27(4), 57–63.
Aviram et al. (2023). Evaluating sex differences in efficacy, safety, and pharmacokinetics in patients treated with cannabis by a metered-dose inhaler. Pharmaceuticals, 16(10).
Kumric et al. (2023). Cannabinoids and blood pressure regulation: Insights from chronic pain management studies. Frontiers in Pharmacology.
Relevance: Explores CBD’s hypotensive effects in chronic pain patients, particularly in hypertensive individuals, highlighting the need for careful monitoring. Adds depth to safety considerations for cannabis use.mdpi.com
Shamabadi et al. (2023). Cannabis use and mental health outcomes in chronic pain patients: An umbrella review. Journal of Psychiatric Research.
Relevance: Highlights risks of depression and suicidality associated with cannabis use, particularly THC, in chronic pain patients. Critical for balanced content on risks and mental health impacts.mdpi.com
Felice et al. (2023). Long-term effects of cannabis on memory and cognition in chronic pain management. Neuropsychopharmacology.
Relevance: Demonstrates potential memory deficits from THC use, particularly in adolescents, but notes improved cognitive performance with medical cannabis in some contexts. Useful for discussing long-term safety.mdpi.com
Bell et al. (2024). Chronic Pain and Cannabis-Based Medicines. Cannabis and Cannabinoid Research, 9(2), 669–687.
Karimi-Haghighi et al. (2025). Improvement in Cognitive Function in Chronic Pain: Therapeutic Potential of the Endocannabinoid System. Molecular Neurobiology, 62(7), 8977–8985.
Cortez-Resendiz et al. (2025). The Pharmacology of Cannabinoids in Chronic Pain. Cannabis and Cannabinoid Research.
Castelli et al. (2023). Characterization of Cannabis-Based Products for Pain Management. Frontiers in Pharmacology, 14, 1237485.
Relevance: Analyzes various cannabis products (oils, flowers) for pain management, offering insights into product selection and efficacy. Useful for practical guidance on forms of cannabis.pubmed.ncbi.nlm.nih.gov
Pires et al. (2024). Cannabis-Based Products Marketed for Medical and Non-Medical Use Purchased in Portugal. Molecules, 29(12), 2737.
Zelaya et al. (2023). Chronic Pain and High-Impact Chronic Pain Among U.S. Adults, 2019. NCHS Data Brief, (390), 1–8.
Kodila et al. (2023). Critical Windows: Exploring the Association Between Perinatal Trauma, Epigenetics, and Chronic Pain. The Neuroscientist.
Agency for Healthcare Research and Quality (2025). Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain. Effective Health Care Program.
Wang et al. (2023). Cannabis use preferences and decision-making among a cross-sectional cohort of medical cannabis patients with chronic pain. Journal of Pain Research.
Boehnke et al. (2023). Medical cannabis patterns of use and substitution for opioids & other pharmaceutical drugs. Harm Reduction Journal, 20(1), 45.
Lucas et al. (2023). Medical cannabis and its impact on opioid use in chronic pain patients. Harm Reduction Journal, 20(1), 9.
Mahabir et al. (2023). Medical cannabis use in the United States: A retrospective database study. Journal of Cannabis Research, 5(1), 32.
Stith et al. (2023). Cannabis and improved neurocognitive performance in chronic pain patients. Journal of Cannabis Research.
Hinckley et al. (2023). Cannabis use and depression severity in chronic pain patients. Journal of Psychiatric Research.
Barke et al. (2023). Chronic pain in the ICD-11: New diagnoses and implications for cannabis treatment. Clinical Psychology in Europe, 4, e9933.
Nicolson et al. (2023). What is the association between childhood adversity and subsequent chronic pain in adulthood? BJA Open, 6, 100139.
Treede et al. (2023). Chronic pain as a symptom or a disease: The IASP classification of chronic pain for the ICD-11. Pain, 160, 19–27.
Häuser et al. (2023). Chronic pain and patient satisfaction with pain treatment in Germany. Schmerz, 28, 483–492.
Sagar et al. (2023). Longitudinal study of medical cannabis and neurocognitive performance in chronic pain. Journal of Cannabis Research.
Merlin et al. (2023). Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV. AIDS Care, 28(12), 1506–1515.
Mehta et al. (2023). Systematic Review of Pharmacologic Treatments of Pain After Spinal Cord Injury. Archives of Physical Medicine and Rehabilitation, 97(8), 1381–1391.
Mendoza & McPherson (2023). Knowledge, skills, and attitudes regarding the use of medical cannabis in the hospice population. Journal of Palliative Medicine.
